Mahendra Pratap Singh Selected Research

cypermethrin (alphamethrin)

9/2021	Involvement of Peroxiredoxin-3, Thioredoxin-2, and Protein Deglycase-1 in Cypermethrin-Induced Parkinsonism.
6/2021	Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins.
1/2018	Ibuprofen Protects from Cypermethrin-Induced Changes in the Striatal Dendritic Length and Spine Density.
1/2018	Cypermethrin Activates Autophagosome Formation Albeit Inhibits Autophagy Owing to Poor Lysosome Quality: Relevance to Parkinson's Disease.
12/2016	Ibuprofen abates cypermethrin-induced expression of pro-inflammatory mediators and mitogen-activated protein kinases and averts the nigrostriatal dopaminergic neurodegeneration.
12/2015	Cyclosporine A and MnTMPyP Alleviate α-Synuclein Expression and Aggregation in Cypermethrin-Induced Parkinsonism.
4/2015	Cypermethrin-induced nigrostriatal dopaminergic neurodegeneration alters the mitochondrial function: a proteomics study.
12/2014	Cypermethrin alters the status of oxidative stress in the peripheral blood: relevance to Parkinsonism.

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Mahendra Pratap Singh Research Topics

Disease

28	Parkinson Disease (Parkinson's Disease) 07/2022 - 04/2006
17	Parkinsonian Disorders (Parkinsonism) 09/2021 - 04/2012
6	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 04/2010
5	Inflammation (Inflammations) 01/2018 - 06/2010
4	Breast Neoplasms (Breast Cancer) 05/2011 - 01/2007
3	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2022 - 02/2012
3	Neoplasms (Cancer) 10/2019 - 07/2019
3	B-Cell Lymphoma (Lymphoma, B Cell) 01/2018 - 11/2012
2	Necrosis 06/2021 - 12/2016
2	Neuroblastoma 01/2020 - 01/2018
2	Tremor (Tremors) 01/2016 - 02/2012
2	MPTP Poisoning 12/2015 - 12/2013
2	Neuroinflammatory Diseases 04/2012 - 04/2012
1	Alzheimer Disease (Alzheimer's Disease) 07/2022
1	Constipation 03/2021
1	Dysbiosis 03/2021
1	Pseudomyxoma Peritonei 12/2020
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 07/2019
1	Tuberous Sclerosis (Bourneville's Disease) 01/2018
1	Genetic Predisposition to Disease (Genetic Predisposition) 12/2017
1	Septic Shock (Toxic Shock Syndrome) 10/2017
1	Psoas Abscess 06/2016

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 09/2021 - 09/2007
10	ManebIBA 01/2020 - 04/2006
10	ParaquatIBA 01/2020 - 04/2006
8	cypermethrin (alphamethrin)IBA 09/2021 - 12/2014
6	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 02/2012
5	SynucleinsIBA 03/2021 - 12/2015
5	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2020 - 10/2008
5	Caffeine (No Doz)FDA LinkGeneric 01/2019 - 05/2008
4	SilymarinIBA 02/2020 - 06/2010
4	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 02/2020 - 04/2010
4	AntioxidantsIBA 01/2020 - 04/2006
4	ProteomeIBA 04/2015 - 05/2007
4	Nicotine FDA Link 12/2013 - 05/2008
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2020 - 04/2012
3	XenobioticsIBA 01/2020 - 10/2008
3	ResveratrolIBA 01/2020 - 04/2012
3	EnzymesIBA 01/2020 - 01/2009
3	MelatoninIBA 12/2013 - 03/2011
2	ThioredoxinsIBA 09/2021 - 01/2020
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2021 - 01/2018
2	Mitogen-Activated Protein KinasesIBA 06/2021 - 12/2016
2	Pharmaceutical PreparationsIBA 03/2021 - 12/2016
2	Biomarkers (Surrogate Marker)IBA 10/2019 - 02/2010
2	Caspase 3 (Caspase-3)IBA 01/2018 - 12/2016
2	Caspase 9IBA 01/2018 - 11/2012
2	Ibuprofen (Motrin)FDA LinkGeneric 01/2018 - 12/2016
2	UbiquitinIBA 01/2016 - 02/2012
2	Polylactic Acid-Polyglycolic Acid CopolymerIBA 12/2015 - 12/2013
2	ManganeseIBA 12/2015 - 12/2013
2	Mn(III) 5,10,15,20- tetrakis(N- methylpyridinium- 2- yl)porphyrinIBA 12/2015 - 08/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2014 - 08/2010
2	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 10/2008 - 01/2007
1	polyglutamineIBA 07/2022
1	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 09/2021
1	Free RadicalsIBA 09/2021
1	Conditioned Culture MediaIBA 06/2021
1	Matrix Metalloproteinases (MMPs)IBA 06/2021
1	Protein Kinase CIBA 06/2021
1	p38 Mitogen-Activated Protein KinasesIBA 06/2021
1	Neurotransmitter Agents (Neurotransmitter)IBA 03/2021
1	MucinsIBA 12/2020
1	quinone (benzoquinone)IBA 01/2020
1	NADP (NADPH)IBA 01/2020
1	Oxidoreductases (Dehydrogenase)IBA 01/2020
1	torinIBA 01/2018
1	Autophagy-Related Protein 12IBA 01/2018
1	Sirtuin 1IBA 01/2018
1	bafilomycin A1IBA 01/2018
1	Interleukin-4 (Interleukin 4)IBA 01/2018
1	protein kinase PIBA 01/2018
1	Lysosomal Membrane ProteinsIBA 01/2018
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2018
1	trans-sodium crocetinate (crocetin)IBA 01/2018
1	Beclin-1IBA 01/2018
1	InterferonsIBA 01/2018
1	Sirolimus (Rapamycin)FDA Link 01/2018
1	SirtuinsIBA 01/2018
1	Adenosine Monophosphate (AMP)IBA 01/2018
1	Adenine FDA LinkGeneric 01/2018
1	Autophagy-Related Protein-1 HomologIBA 01/2018
1	TOR Serine-Threonine KinasesIBA 01/2018
1	Vinblastine (Vinblastine Sulfate)FDA Link 01/2018
1	LipopolysaccharidesIBA 10/2017
1	Methionine Sulfoxide ReductasesIBA 10/2017
1	PesticidesIBA 01/2017
1	MetalsIBA 01/2017
1	Apoptosis Regulatory ProteinsIBA 12/2016
1	Cytochromes c (Cytochrome c)IBA 12/2016
1	JNK Mitogen-Activated Protein KinasesIBA 12/2016
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 12/2016
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2016
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 01/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016
1	PolyphenolsIBA 01/2016

Therapy/Procedure

2	Laparotomy 10/2019 - 10/2019
2	Therapeutics 10/2019 - 01/2017
1	Rejuvenation 01/2017